Tapering immunosuppression in recipients of living donor kidney transplants
نویسندگان
چکیده
منابع مشابه
Tapering immunosuppression in recipients of living donor kidney transplants.
We have previously suggested that the in vitro donor-specific cytotoxic T-lymphocyte precursor (CTLp) assay can guide us to identify patients in which the immunosuppressive load can be tapered. In a clinical trial we had observed that a low (<10/10(6) PBMC) frequency of these CTLp was predictive for an uneventful rejection-free clinical course in patients that were converted from calcineurin in...
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CONTEXT Although life-saving, liver transplantation burdens children with lifelong immunosuppression and substantial potential for morbidity and mortality. OBJECTIVE To establish the feasibility of immunosuppression withdrawal in pediatric living donor liver transplant recipients. DESIGN, SETTING, AND PATIENTS Prospective, multicenter, open-label, single-group pilot trial conducted in 20 st...
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The disparity between kidney transplant candidates and donors necessitates innovations to increase organ availability. Transporting kidneys allows for living donors and recipients to undergo surgery with a familiar transplant team, city, friends, and family. The effect of shipping kidneys and prolonged cold ischemia time (CIT) with living donor transplantation outcomes is not clearly known. Thi...
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OBJECTIVE To review a single center's experience and outcome with living donor transplants. SUMMARY BACKGROUND DATA Outcome after living donor transplants is better than after cadaver donor transplants. Since the inception of the authors' program, they have performed 2,540 living donor transplants. For the most recent cohort of recipients, improvements in patient care and immunosuppressive pr...
متن کاملWeaning of immunosuppression in long-term recipients of living related renal transplants: a preliminary study.
A LTHOUGH renal transplantation continues to be associated with increasingly good shortand longterm graft survival, there remains a need for continued chronic immunosuppression and this can lead to significant complications. I 3 This has prompted the evaluation of withdrawal or modification of immunosuppression by several investigators with varying results.4•5 Emerging data proposing dendritic ...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2004
ISSN: 1460-2385
DOI: 10.1093/ndt/gfh1044